Chonluten
aka T-34 · EDG peptide · Glu-Asp-Gly · Bronchogen
Mechanism
Chonluten is a synthetic tripeptide (Glu-Asp-Gly, EDG) short-peptide bioregulator developed by Vladimir Khavinson and colleagues at the St. Petersburg Institute of Bioregulation and Gerontology. It targets the bronchopulmonary system, where the Khavinson group reports it modulates gene expression in respiratory epithelium via direct peptide-DNA interaction in promoter regions. Evidence is limited to preclinical and small clinical studies from a single Russian research group; it is not FDA-approved and has no Western clinical validation.
Studied uses
- bronchial and respiratory mucosa research (research only)
- antioxidant and anti-inflammatory signaling models (preclinical)
- age-related respiratory function studies (single-group research)
Identification
| CAS number | 75007-24-8 |
|---|---|
| Molecular formula | C11H17N3O8 |
| Sequence | EDG |
| Typical dose | No established clinical dosing; vendor research protocols commonly cite 1-2 mg/day subcutaneous or sublingual |
| Half-life | Not characterized in peer-reviewed pharmacokinetic literature; short-peptide bioregulators are presumed to clear rapidly (minutes) |
Safety
Not FDA-approved for human therapeutic use. A Russian/Khavinson research peptide with little independent Western safety or efficacy data; sold grey-market for research use only. Not evaluated by WADA.
Vendors selling Chonluten
| Vendor | Size | Price | Listed purity | Trust |
|---|---|---|---|---|
| BioLongevity Labs | 20 mg | $69.97 | — | 96 |
| Peptide Plugs | 20 mg | $50.00 | — | 89 |
| Verified Peptides | 20 mg | $55.00 | — | 86 |
Research
This study evaluates the effects of five different peptides, the Epitalon ® tetrapeptide, the Vilon ® dipeptide, the Thymogen ® dipeptide, the Thymalin ® peptide complex, and the Chonluten ® tripeptide, as regulators of inflammatory and proliferative processes in the human monocytic THP-1, which is a human leukemia mon…
source →Ultrashort peptides (USPs), consisting of 2-7 amino-acid residues, are a group of signaling molecules that regulate gene expression and protein synthesis under normal conditions in various diseases and ageing. USPs serve as a basis for the development of drugs with a targeted mechanism of action.
source →There is a vast practice of using antimalarial drugs, RAS inhibitors, serine protease inhibitors, inhibitors of the RNA-dependent RNA polymerase of the virus and immunosuppressants for the treatment of the severe form of COVID-19, which often occurs in patients with chronic diseases and older persons.
source →