Crystagen
aka EDP · Glu-Asp-Pro
Mechanism
Crystagen is a synthetic tripeptide (Glu-Asp-Pro, EDP) short-peptide bioregulator developed by Vladimir Khavinson and colleagues at the St. Petersburg Institute of Bioregulation and Gerontology as an immune-system bioregulator. The Khavinson group reports it modulates immune-cell gene expression and chromatin organization, influencing T-cell, B-cell, and thymic epithelial activity via direct peptide-DNA interaction. Evidence is confined to single-group preclinical and small clinical studies; it is not FDA-approved and lacks independent Western validation. No CAS Registry Number is listed for this peptide in major chemical databases.
Studied uses
- immune-cell gene regulation research (research only)
- thymic and lymphocyte activity models (preclinical)
- immunosenescence and age-related immune decline studies (single-group research)
Identification
| Molecular formula | C14H21N3O8 |
|---|---|
| Sequence | EDP |
| Typical dose | No established clinical dosing; vendor research protocols commonly cite 1-2 mg/day subcutaneous or sublingual |
| Half-life | Not characterized in peer-reviewed pharmacokinetic literature; short-peptide bioregulators are presumed to clear rapidly (minutes) |
Safety
Not FDA-approved for human therapeutic use. A Russian/Khavinson research peptide with little independent Western safety or efficacy data; sold grey-market for research use only. Not evaluated by WADA.
Vendors selling Crystagen
| Vendor | Size | Price | Listed purity | Trust |
|---|---|---|---|---|
| Certified Peptides | 20 mg | $105.00 | — | 62 |
Research
Ultrashort peptides (USPs), consisting of 2-7 amino-acid residues, are a group of signaling molecules that regulate gene expression and protein synthesis under normal conditions in various diseases and ageing. USPs serve as a basis for the development of drugs with a targeted mechanism of action.
source →Vilon, Timogen, Crystagen and R-1 short peptides possess various immunoprotective effects in spleen during its ageing. Both R-1 and Vilon peptides activate T-helpers.
source →