Vilon
aka Lys-Glu
Mechanism
Vilon is a synthetic dipeptide (Lys-Glu / KE) from the Khavinson bioregulator series, originally derived from thymus extracts and studied in Russian preclinical models as an immunomodulator and geroprotector. Not FDA-approved; all published evidence originates from a single research group.
Identification
| CAS number | 45234-02-4 |
|---|---|
| Molecular formula | C11H21N3O5 |
| Sequence | KE |
| Typical dose | 5 mg/day subcutaneous for 10-12 day cycles, repeated every 3-6 months (research use only) |
| Half-life | ~30 minutes (estimated; dipeptide subject to rapid hydrolysis) |
Vendors selling Vilon
| Vendor | Size | Price | Listed purity | Trust |
|---|---|---|---|---|
| BioLongevity Labs | 20 mg | $79.97 | — | 96 |
| Orbitrex Peptides | 20 mg | $49.99 | — | 95 |
| Peptide Tech | 20 mg | $38.99 | — | 94 |
| Peptidology | 20 mg | $54.99 | — | 89 |
| Peptide Plugs | 20 mg | $50.00 | — | 89 |
| Verified Peptides | 20 mg | $60.00 | — | 86 |
| Peptidegurus | 20 mg | — | — | 84 |
| Cocer Peptides | 20 mg | $160.00 | — | 82 |
| Certified Peptides | 20 mg | $105.00 | — | 62 |
| Biotech Peptides | 20 mg | $61.00 | — | — |
| Core Peptides | 20 mg | $74.00 | — | — |
| Genetic Peptide | 20 mg | $65.00 | — | — |
| Peptira | — | $59.00 | — | — |
| Platinum Lion | — | $64.99 | — | — |
| Wellness Peptides | — | $60.00 | — | — |
Research
Epitalon, also known as Epithalon or Epithalone, is a tetrapeptide, Ala-Glu-Asp-Gly (AEDG), which was synthesized based on the amino acids composition of Epithalamin, a bovine pineal gland extract, prior to its discovery in pineal gland polypeptide complex solution.
source →The hyoid bone has been identified as sexually dimorphic in various populations. The current study is a forerunner analysis that used three-dimensional multidetector computed tomography (3D MDCT) images of the hyoid bone to examine sexual dimorphism in the Egyptian population.
source →Understanding the dysregulation of complex biological pathways is essential for uncovering molecular mechanisms and identifying novel therapeutic opportunities for complex diseases.
source →The study aimed to evaluate auditory spatial perception in individuals with and without recreational noise exposure using Virtual Acoustic Space Identification. A standard group comparison design using purposive sampling was conducted on 60 normal-hearing participants aged 18-30.
source →With more and more data being collected, modern network representations exploit the complementary nature of different data sources as well as similarities across patients.
source →In the present study, on the one hand, the epigenetic modification of condensed "old" chromatin was determined, and on the other hand, the influence of peptide bioregulators (Ala-Glu-Asp-Gly-Epitalon; Lys-Glu-Asp-Ala-Livagen; Ala-Glu-Asp-Pro - Cortagen and Lys-Glu - Vilon) on condensed chromatin in lymphocytes from old…
source →It was shown that KE peptide (Lys-Glu, vilon) has immunomodulatory, oncostatic and geroprotective effects. The aim of this work is to evaluate the effect of the KE peptide on gene expression and protein synthesis of SIRT1, PARP1, PARP2 during aging of human mesenchymal stem cells (MSC).
source →With an increasing aging population, the burden of age-related diseases magnifies. To alleviate this burden, geroprotection has been an area of intense research focus with the development of pharmacological interventions that target lifespan and/or healthspan.
source →This study evaluates the effects of five different peptides, the Epitalon ® tetrapeptide, the Vilon ® dipeptide, the Thymogen ® dipeptide, the Thymalin ® peptide complex, and the Chonluten ® tripeptide, as regulators of inflammatory and proliferative processes in the human monocytic THP-1, which is a human leukemia mon…
source →The article presents data on the use of peptide bioregulators of cell homeostasis and the protective functions of the body in various dental diseases and pathology of organs and tissues of the maxillofacial region.
source →A multi-center non-interventional, in-vitro trial for evaluation of concordance of the results for Human Epidermal Growth Factor Receptor 2 (HER2) expression by the Immunohistochemical (IHC) method in pathological samples collected from participants with breast cancer.
source →