AHK-Cu
aka AHK Copper Peptide
Mechanism
AHK-Cu is a copper-binding tripeptide (Ala-His-Lys-Cu) structurally related to GHK-Cu, studied in dermatological research for its role in extracellular matrix remodeling and hair follicle signaling.
Identification
| CAS number | 682809-81-0 |
|---|---|
| Molecular formula | C15H24ClCuN6O4 |
| Sequence | AHK |
| Typical dose | 0.01–0.1% topical solution (100–1000 mcg/mL); injectable research use 0.1–1.0 mg/mL subcutaneous |
| Half-life | ~4–6 hours (dermal tissue; no formal human PK study published) |
Vendors selling AHK-Cu
| Vendor | Size | Price | Listed purity | Trust |
|---|---|---|---|---|
| Glacier Aminos | — | $64.99 | — | 99 |
| Orbitrex Peptides | — | $170.00 | — | 95 |
| Ion Peptide | — | $65.00 | — | 95 |
| Ion Peptide | — | $29.00 | — | 95 |
| Peptide Tech | 100 mg | $53.99 | — | 94 |
| Mile High Compounds | — | $79.99 | — | 94 |
| Skye Peptides | 1000 mg | $69.00 | — | 90 |
| Peptidology | 100 mg | $119.99 | — | 89 |
| Peptide Plugs | 100 mg | $50.00 | — | 89 |
| Cocer Peptides | 100 mg | $120.00 | — | 82 |
| Mandy | 50 mg | $20.00 | — | 43 |
| NG Peptide | 100 mg | $30.00 | — | — |
| Ruo Bio | 100 mg | $46.00 | — | — |
| Biotech Peptides | 200 mg | $192.00 | — | — |
| Core Peptides | 200 mg | $203.00 | — | — |
| Modern Research Peptides | 100 mg | $69.99 | — | — |
| Polaris Peptides | — | $45.00 | — | — |
| S1 Research | — | $45.00 | — | — |
Research
Hair serves essential functions, including mechanical sensing, head protection, and body temperature regulation, while also playing a significant role in human aesthetics.
source →Divalent trace metals (TM), especially copper (Cu), cobalt (Co) and zinc (Zn), are recognized as essential microelements for tissue homeostasis and regeneration.
source →One of the side effects of oral antiaging retinoids is increased hair shedding. Retinoids promote the expression of TGF-β2 from fibroblasts, which stimulate collagen expression but silences keratinocytes.
source →Current treatment modalities are limited in their approach and success for hair loss. QR 678 & QR 678 Neo are new formulations, consisting of a combination of growth factors and peptides.
source →The tripeptide-copper complex, described as a growth factor for various kinds of differentiated cells, stimulates the proliferation of dermal fibroblasts and elevates the production of vascular endothelial growth factor, but decreased the secretion of transforming growth factor-beta1 by dermal fibroblasts.
source →