DSIP
aka Delta Sleep-Inducing Peptide
Mechanism
DSIP is a nonapeptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) isolated in 1977 from the cerebral blood of rabbits during electrically induced sleep. Mechanism remains uncertain and the clinical evidence base is weak. Not FDA-approved — research use only.
Identification
| CAS number | 62568-57-4 |
|---|---|
| Molecular formula | C35H48N10O15 |
| Sequence | WAGGDASGE |
| Typical dose | 100-250 mcg/day subcutaneous, administered ~3 hours before bedtime; some studies used 25 nmol/kg (~21.4 mcg/kg) |
| Half-life | ~15 minutes in vitro; ~4-5 minutes in animal studies; human elimination data limited |
Vendors selling DSIP
| Vendor | Size | Price | Listed purity | Trust |
|---|---|---|---|---|
| Peptide Partners | 10 mg | $75.00 | — | 99 |
| Glacier Aminos | 10 mg | $59.99 | — | 99 |
| Moglabs | 5 mg | $26.00 | — | 96 |
| Moglabs | 5 mg | $38.00 | — | 96 |
| BioLongevity Labs | 5 mg | $55.97 | — | 96 |
| Orbitrex Peptides | 10 mg | $59.99 | — | 95 |
| Profound Aminos | 5 mg | $39.00 | — | 95 |
| Ion Peptide | — | $45.00 | — | 95 |
| Licensed Peptides | 5 mg | $53.99 | — | 95 |
| Peptide Tech | 5 mg | $23.99 | — | 94 |
| Mile High Compounds | — | $49.99 | — | 94 |
| Amino Club | — | $29.99 | — | 93 |
| Riptide Wellness | — | $44.99 | — | 92 |
| Hydro Research Peptides | 5 mg | $0.45 | — | 91 |
| Skye Peptides | 5 mg | $49.00 | — | 90 |
| Peptidology | 15 mg | $58.99 | — | 89 |
| Peptide Plugs | 10 mg | $40.00 | — | 89 |
| Qihang Peptide | — | — | — | 87 |
| Verified Peptides | 10 mg | $49.00 | — | 86 |
| EZ Peptides | 10 mg | $58.00 | — | 85 |
| Simple Peptide | 5 mg | $35.00 | — | 85 |
| Peptidegurus | 5 mg | — | — | 84 |
| Ascension Peptides | 10 mg | $60.00 | — | 84 |
| Cocer Peptides | 10 mg | $120.00 | — | 82 |
| Blank Peptides | 10 mg | $65.00 | — | 81 |
| OROS Research | 5 mg | — | — | 79 |
| Texpeptide | 5 mg | $30.00 | — | 70 |
| Crystal Peptides | 5 mg | $29.99 | — | 66 |
| Qing Li Peptide | — | — | — | 63 |
| Qing Li Peptide | 5 mg | — | — | 63 |
| Certified Peptides | 5 mg | $42.00 | — | 62 |
| Nox Amino | 10 mg | $39.00 | — | 55 |
| Peptiatlas | — | — | — | 51 |
| DongCheng Peptide | — | — | — | 46 |
| Mandy | 5 mg | $33.00 | — | 43 |
| HongDa Peptide | — | $49.00 | — | 43 |
| zztai Peptide Ltd | — | — | — | 43 |
| MJT peptides | 5 mg | $43.00 | — | 39 |
| NG Peptide | 5 mg | $35.00 | — | — |
| AMC Essentials | 5 mg | $29.99 | — | — |
| Alpha Omega | 5 mg | $35.00 | — | — |
| Arcane Peptides | 5 mg | $30.00 | — | — |
| Atomik Labz | 10 mg | $53.00 | — | — |
| Atomik Labz | 10 mg | $45.00 | — | — |
| Atomik Labz | 5 mg | $43.00 | — | — |
| Atomik Labz | 5 mg | $35.00 | — | — |
| Biotech Peptides | 5 mg | $44.00 | — | — |
| Bulk Peptides | 5 mg | $140.00 | — | — |
| Core Peptides | 5 mg | $41.00 | — | — |
| Felix Chemical Supply | 5 mg | $39.99 | — | — |
| Felix Chemical Supply | 10 mg | $59.99 | — | — |
| Flawless Compounds | — | — | — | — |
| Genetic Peptide | 5 mg | $50.00 | — | — |
| Genetic Peptide | 10 mg | $50.00 | — | — |
| Ignite Peptides | 5 mg | $30.00 | — | — |
| Kimera Chems | 5 mg | $31.99 | — | — |
| Lumi Peptides | — | $35.00 | — | — |
| Modern Research Peptides | 10 mg | $42.99 | — | — |
| Nextech Labs | 10 mg | $45.00 | — | — |
| Nova Peptides | 5 mg | $34.99 | — | — |
| Oasis Labs | 5 mg | $37.50 | — | — |
| Oneday Compounds | 5 mg | $44.99 | — | — |
| Paramount Peptides | 5 mg | $50.00 | — | — |
| Paramount Peptides | 10 mg | $65.00 | — | — |
| Peptide Crafters | 5 mg | $30.00 | — | — |
| Peptira | — | $89.00 | — | — |
| Pepvida Labs | 5 mg | $35.00 | — | — |
| Polaris Peptides | 5 mg | $40.00 | — | — |
| Puratek Peptides | 10 mg | $31.45 | — | — |
| S1 Research | 5 mg | $24.00 | — | — |
| Solution Peptides | 10 mg | $53.00 | — | — |
| Solution Peptides | 10 mg | $45.00 | — | — |
| Solution Peptides | 5 mg | $43.00 | — | — |
| Solution Peptides | 5 mg | $35.00 | — | — |
| Soma Peptides | — | $79.00 | — | — |
| Soma Peptides | 6 mg | $39.00 | — | — |
| Southern Aminos | 5 mg | $36.75 | — | — |
| True Peptide | 15 mg | $64.00 | — | — |
| True Peptide | 5 mg | $28.00 | — | — |
| Welli Labs | — | $25.99 | — | — |
| Wellness Peptides | — | $32.00 | — | — |
Research
Therapeutic peptides are short chains of amino acids used to treat metabolic and endocrine conditions such as obesity and type 2 diabetes.
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source →Background Pichia pastoris -secreted delta sleep inducing peptide and crossing the blood-brain barrier peptides (DSIP-CBBBP) fusion peptides holds significant promise for its potential sleep-enhancing and neurotransmitter balancing effects.
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