BPC-157
aka Body Protection Compound 157 · PL 14736
Healing & Recovery research-only
Mechanism
Pentadecapeptide derived from a gastric protective protein. Studied for tendon/ligament healing, GI tract repair, and angiogenesis via VEGFR2 pathway interaction.
Studied uses
- gastrointestinal ulcer healing (animal studies)
- post-surgical recovery (research only)
- tendon and ligament injury recovery
Identification
| CAS number | 137525-51-0 |
|---|---|
| Molecular formula | C62H98N16O22 |
| Sequence | GEPPPGKPADDAGLV |
| Typical dose | 250–500 mcg/day subcutaneous (research only — not FDA approved for human use) |
| Half-life | ~30 minutes (parenteral) |
Safety
Not FDA-approved for human therapeutic use. WADA does not currently prohibit BPC-157 but research-use only status applies in most jurisdictions.
Vendors selling BPC-157
| Vendor | Size | Price | Listed purity | Trust |
|---|---|---|---|---|
| Peptide Partners | — | — | — | 65 |
| Nuscience Peptides | — | — | — | 60 |
| Elite Research USA | — | — | — | 53 |
| Skye Peptides | — | — | — | 53 |
| Crush Research | — | — | — | 46 |
| Kimera Chems | — | — | — | 46 |
| Vril Peptides | — | — | — | 43 |
| Peptide Sciences | — | — | — | 26 |
Research
Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing.
McGuire FP, Martinez R, Lenz A, et al. · Curr Rev Musculoskelet Med (2025) · review
source → Injectable Therapeutic Peptides-An Adjunct to Regenerative Medicine and Sports Performance?
DeFoor MT, Dekker TJ · Arthroscopy (2025) · review
source → Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review.
Vasireddi N, Hahamyan H, Salata MJ, et al. · HSS J (2025) · review
source → Multifunctionality and Possible Medical Application of the BPC 157 Peptide-Literature and Patent Review.
Józwiak M, Bauer M, Kamysz W, et al. · Pharmaceuticals (Basel) (2025) · review
source → Effect of BPC-157 on Symptoms in Patients with Interstitial Cystitis: A Pilot Study.
Lee E, Walker C, Ayadi B · Altern Ther Health Med (2024) ·
source → Intra-Articular Injection of BPC 157 for Multiple Types of Knee Pain.
Lee E, Padgett B · Altern Ther Health Med (2021) ·
source → Stable Gastric Pentadecapeptide BPC 157 and Wound Healing.
Seiwerth S, Milavic M, Vukojevic J, et al. · Front Pharmacol (2021) · review
source → Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing.
Gwyer D, Wragg NM, Wilson SL · Cell Tissue Res (2019) · review
source → BPC 157 and Standard Angiogenic Growth Factors. Gastrointestinal Tract Healing, Lessons from Tendon, Ligament, Muscle and Bone Healing.
Seiwerth S, Rucman R, Turkovic B, et al. · Curr Pharm Des (2018) · review
source → The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration.
Chang CH, Tsai WC, Lin MS, et al. · J Appl Physiol (1985) (2011) ·
source →